Medication Treatment

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Medication Treatment

There are six classes of cholesterol lowering medications. Sometimes a combination of medications is needed to achieve optimal cholesterol and triglyceride levels.

Cholesterol Lowering Drugs Administration Recommendations
HMG Co-A Reductase Inhibitors (Statins)
  • Atorvastatin (Lipitor)
  • Fluvastatin (Lescol)
  • Fluvastatin ER (Lescol XL)
  • Lovastatin (Mevacor)
  • Pravastatin (Pravachol)
  • Rosuvastatin (Crestor)
  • Simvastatin (Zocor)
Take lovastatin with food. Other statins may be taken with or without food. Many statins work best when taken in the evening, but these medications can be taken any time during the day.
Cholesterol Absorption Inhibitor
Ezetimibe (Zetia)
May be taken with or without food
Fibrates
  • Fenofibrate (Tricor, Lofibra, Triglide)
  • Fenofibrate Micronized Capsules (Lofibra, Antara)
  • Gemfibrozil (Lopid)
Take Lofibra once daily with meals. Antara, Triglide, and Tricor can be taken once daily with or without food. Take gemfibrozil % hour before morning and evening meals.
  • Bile Acid Binding Resins
  • Cholestyramine (Questran)
  • Colestipol (Colestid)
  • Colesevelam (Welchol)
Mix powder or granules with 6 ounces of liquid. Take tablets with water. Take at mealtime. Take other medications 1 hour before or 4 hours after medications from this group.
Omega-3 Acid Ethyl Esters
  • DHA & EPA (Omacor)
Docosahexaenoic acid Eicosapentaenoic acid
Take with food
May be taken once daily or dose may be divided into two doses.
Niacin
  • Immediate release niacin (Niacor)
  • Extended Release (Niaspan)
  • Controlled Release (Slo-Niacin)
Take immediate release niacin with meals. Take slow release niacin at bedtime with a low fat snack. Do not break, crush or chew.
Combination Products
  • Atorvastatin/amlodipine (Caduet)
  • Pravastatin/ buffered aspirin (Pravigard PAC)
  • Ezetimibe/simvastatin (Vytorin)
May be taken once daily with or without food.